TABLE 3

Ray 1 axon defects

Ray axon morphology
Embedded ImageEmbedded ImageEmbedded ImageEmbedded ImageEmbedded ImageEmbedded ImageEmbedded Image
GenotypeWild type (%)Wandering (%)Ectopic outgrowth (%)No ventral turning (%)Anteriorly ventral turn (%)Bifurcating (%)Cell migration (%)N
him-5(e1490)9720.4228
rax-1(bx126)5111263.38.5274
rax-1(bx132)2016493.98.1405
rax-4(bx139)3924856288
rax-2(bx131)82162100a84
rax-3(bx133)7327b78101
rax-3(bx138)8119b77170
rax-5(bx137)707131017c225
rax-6(bx140)7771648c109
bx141732768
sax-2(bx130)100200
unc-27(bx124)97912153
  • The percentage of sides with ray 1 defect is shown. Defects in the ray 1 process were the most easily scored and most likely to be abnormal. With the exception of rax-1 and rax-4, ray commissures of the posterior rays were usually present in mutants.

  • a 80% of males have more than 8 pkd-2∷GFP positive neurons in the tail, in addition to the anterior mispositioned ray neuons.

  • b Ray axons from 27% and 19%of sides in bx133 and bx138 mutant, respectively, fail to make the ventral turn when the neurons are mispositioned anteriorly. The rest of the neurons extend posteriorly-directed axons.

  • c The neurons of fused rays form cluster in the lumbar ganglion. Axon defects and cell migration defect are counted separately.