TABLE 4

Interactions of new mutations with class A and class B synMuv mutations

Double mutant with class ADouble mutant with class B
Single mutantlin-15A(n767)lin-38 (n751)lin-15B(n744)lin-35(n745)
% >3 vulval fates (n)Ave. no. vulval fates (±SE)% >3 vulval fates (n)Ave. no. vulval fates (±SE)% >3 vulval fates (n)Ave. no. vulval fates (±SE)% >3 vulval fates (n)Ave. no. vulval fates (±SE)% >3 vulval fates (n)Ave. no. vulval fates (±SE)
New mutationlin-65(n3441)0 (35)3.0 (±0)100 (36)5.9 (±0.04)97 (37)5.3 (±0.13)4.3 (23)3.02 (±0.02)NDND
lin(n3628)0 (37)3.0 (±0)71 (41)3.9 (±0.14)92 (24)4.4 (±0.15)2.7 (37)3.01 (±0.01)0 (31)3.0 (±0)
mep-1(n3703)2.5 (40)3.01 (±0.01)100 (29)6.0 (±0.19)100 (36)5.9 (±0.29)0 (21)3.0 (±0)0 (25)3.0 (±0)
ark-1(n3701)0 (33)3.0 (±0)77 (30)4.5 (±0.20)56 (34)3.8 (±0.14)7.8 (26)3.06 (±0.04)7.4 (27)3.07 (±0.05)
gap-1(ga133)3.1 (32)3.02 (±0.02)58 (38)3.6 (±0.11)76 (37)4.4 (±0.17)0 (29)3.0 (±0)0 (30)3.0 (±0)
sli-1(n3538)0 (25)3.0 (±0)93 (28)4.6 (±0.16)30 (27)3.3 (±0.11)0 (36)3.0 (±0)4.5 (22)3.02 (±0.02)
Class Alin-15A(n767)0 (24)a3.0 (±0)accNDNDcc
lin-38 (n751)0 (27)a3.0 (±0)a0 (32)3.0 (±0)cccc
Class Blin-15B(n744)0 (20)3.0 (±0)NDND100 (33)6.0 (±0)cc
lin-35(n745)0 (48)3.0 (±0)100 (22)6.0 (±0)100 (27)6.0 (±0)0 (26)3.0 (±0)
Class Cmys-1(n3681)8.3 (36)b3.06 (±0.03)b100 (26)b5.04 (±0.14)b91 (45)b4.40 (±0.13)b46 (37)3.38 (±0.08)NDND
trr-1(n3712)13 (89)a3.10 (±0.03)a74 (54)a4.07 (±0.12)a79 (14)a4.14 (±0.23)a50 (38)3.38 (±0.07)63 (41)3.43 (±0.06)
  • New synMuv mutations were separated from lin-15A(n767), and double-mutant strains were constructed as described in materials and methods. Because these mutations cause recessive sterility, mep-1(n3703) and trr-1(n3712) homozygotes were derived from heterozygous parents. mep-1(n3703) homozygotes were recognized as the non-Unc progeny of mep-1(n3703)/nT1 n754 heterozygous parents or the non-Gfp progeny of mep-1(n3703)/nT1[qIs51] heterozygous parents. trr-1(n3712) homozygotes were recognized as the non-Gfp progeny of trr-1(n3712)/mIn1[dpy-10(e128) mIs14] heterozygous parents. The lin(n3628) lin-35 strain was marked with unc-13. ND, not determined.

  • a These data are from Table 1 of Ceol and Horvitz (2004).

  • b These data are from Table 3 of Ceol and Horvitz (2004).

  • c These data are found elsewhere in this table.