I_{1} | I_{2} | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|

T | SD | SD↓ | SD↑ | ∉C.I. | SD | SD↓ | SD↑ | ∉C.I. | ISI | ||

5.23e-08 | 0.89 | 0.92 | 0.95 | 9 | — | — | — | — | — | 2.4e+06 | |

7.82e-07 | 1.27 | 1.09 | 1.35 | 13 | — | — | — | — | — | 7.9e+04 | |

1.29e-05 | 1.20 | 1.06 | 1.24 | 11 | 7.76e-06 | 104.26 | 3.07 | 608.03 | 49 | 5.4e+03 | |

8.76e-06 | 2.20 | 1.80 | 4.47 | 6 | 4.39e-06 | 142.90 | 3.24 | 772.98 | 60 | 2.4e+03 | |

1.49e-04 | 1.57 | 1.34 | 2.47 | 9 | 1.47e-04 | 18.52 | 3.95 | 129.35 | 17 | 2.7e+02 | |

1.66e-03 | 1.46 | 1.29 | 2.08 | 6 | 1.67e-03 | 2.54 | 1.70 | 6.17 | 10 | 2.8e+01 | |

5.43e-04 | 14.72 | 4.34 | 67.70 | 24 | 5.53e-04 | 5.39 | 3.08 | 12.36 | 13 | 6.2e+00 | |

8.57e-03 | 6.02 | 2.76 | 30.61 | 12 | 8.59e-03 | 1.02 | 0.89 | 1.07 | 11 | 1.1e+01 | |

7.49e-02 | 3.25 | 1.89 | 9.92 | 9 | 7.48e-02 | 0.49 | 0.54 | 0.56 | 5 | 5.2e+00 | |

B_{U} | 5.08e-04 | 24.40 | 4.82 | 137.21 | 27 | 5.58e-04 | 22.95 | 3.23 | 135.82 | 29 | — |

B_{DFC} | 2.76e-03 | 23.99 | 5.09 | 137.72 | 22 | 2.91e-03 | 2.10 | 1.52 | 4.83 | 10 | 7.8e+00 |

B_{Si} | 1.14e-02 | 54.21 | 4.28 | 508.81 | 33 | 1.21e-02 | 0.74 | 0.85 | 1.07 | 4 | 1.5e+01 |

B_{Se} | 1.04e-01 | 204.62 | 4.04 | 1859.42 | 58 | 1.18e-01 | 0.44 | 0.48 | 0.50 | 7 | 3.9e+00 |

H_{U} | 8.75e-06 | 2.03 | 1.72 | 3.53 | 8 | 6.64e-06 | 256.77 | 1.78 | 2439.39 | 61 | 2.8e+03 |

H_{DFC} | 1.48e-04 | 1.91 | 1.34 | 3.26 | 14 | 1.51e-04 | 50.34 | 4.45 | 472.74 | 38 | 1.9e+02 |

H_{Si} | 1.67e-03 | 1.54 | 1.29 | 3.19 | 8 | 1.66e-03 | 2.22 | 1.66 | 3.96 | 11 | 2.5e+01 |

H_{Se} | 7.45e-02 | 2.98 | 2.02 | 8.43 | 10 | 7.48e-02 | 0.54 | 0.54 | 0.57 | 8 | 4.2e+00 |

D1 | 4.52e-02 | 79.70 | 3.89 | 468.64 | 41 | 7.27e-02 | 0.56 | 0.54 | 0.57 | 10 | 4.1e+00 |

D2 | 1.42e-02 | 125.43 | 3.99 | 1052.07 | 59 | 1.17e-02 | 0.91 | 0.82 | 0.99 | 12 | 1.0e+01 |

D3 | 1.93e-04 | 15.29 | 3.65 | 52.77 | 23 | 1.90e-04 | 20.17 | 4.13 | 161.01 | 23 | — |

D4 | 1.67e-03 | 1.36 | 1.30 | 3.41 | 5 | 1.67e-03 | 2.96 | 1.68 | 15.78 | 8 | 3.2e+01 |

D5 | 7.03e-05 | 162.84 | 4.72 | 1293.03 | 55 | 8.05e-05 | 12.33 | 3.94 | 58.29 | 19 | — |

P_{U} | 1.29e-09 | 1.33 | 1.26 | 1.31 | 9 | — | — | — | — | — | 4.4e+07 |

P_{DFC} | 8.79e-07 | 1.13 | 1.24 | 1.35 | 4 | 8.72e-07 | 2.46 | 2.15 | 4.84 | 9 | 8.9e+04 |

P_{Si} | 1.08e-04 | 1.42 | 1.24 | 1.44 | 14 | 1.08e-04 | 1.17 | 1.04 | 1.10 | 11 | 6.8e+02 |

P_{F} | 1.46e-04 | 285.69 | 3.04 | 2807.57 | 56 | 1.48e-04 | 1.21 | 1.06 | 1.11 | 14 | 4.6e+02 |

P_{H} | 6.88e-10 | 117.31 | 3.21 | 709.76 | 48 | 1.06e-09 | 30.62 | 4.68 | 166.84 | 27 | — |

For different relationships, given in the

*T*column, 100 independent Monte Carlo estimates of α corresponding to β = 0.1 were made using both methods*I*_{1}and*I*_{2}. Results for*I*_{1}appear on the left and those for*I*_{2}on the right. The description of the quantities given in the columns headed by , SD, SD**↓**, SD**↑**, and**∉**C.I. is given in the text. Values for the best-performing importance-sampling method are in italics. For four relationships—*B*_{U},*D*3,*D*5, and*P*_{H}—neither*I*_{1}nor*I*_{2}provided an acceptable reduction in Monte Carlo error. The ISI column gives the factor by which the best importance-sampling algorithm speeds up the estimation of α relative to the naive Monte Carlo estimator of (6). All calculations were done assuming*L*= 60 loci with minor allele frequencies of*q*= 0.2.