TABLE 4

The influence of mutation rate u and mutational bias κ on estimates of cne, Embedded Image and α

u = 0.5 × 10−9u = 2 × 10−9u = 8 × 10−9
κ = 110.8%10.9%11.0%
6.516.596.67
0.4860.4770.469
κ = 211.3%11.4%11.5%
6.886.957.03
0.4530.4470.441
κ = 311.4%11.5%11.6%
6.957.027.10
0.4520.4460.440
  • The top value in each row gives cne (in percent). The middle value gives Embedded Image [comparable to Nes (hm) in Table 2]. The bottom value gives α, the estimated shape of the gamma distribution. All values are for variance-weighted data from D. miranda, assuming cn = 2.5% and Nes = 0.5 as the border of neutrality.