TABLE 1

Summary of the data and estimates from the strong purifying selection model

EstimateKAKScnPa
Weighted0.086 (0.041/0.136)0.502 (0.340/0.710)0.294 (0.196/0.400)2.86 (2.02/3.43)2.11 (1.28/2.80)23.0 (20.4/24.9)5.41 (2.84/)8.79 (3.91/16.5)3.99 (−123/57.5)
Unweighted0.088 (0.044/0.141)0.478 (0.342/0.626)0.206 (0.124/0.300)2.73 (2.31/3.14)2.48 (1.30/3.76)22.2 (19.9/24.8)3.58 (1.80/29.8)5.24 (0.923/10.3)52.9 (−28.9/93.3)
• All values except for are expressed as percentages. An “infinite” value of corresponds to a zero or negative denominator of Equation 3b. Values in parentheses give the approximate lower and upper fifth percentiles from 1000 bootstrap replicates (see text for details). is the nonsynonymous diversity for species i (i = 1 for D. miranda and 2 for D. pseudoobscura), is the silent diversity for species i, KA and KS are the nonsynonymous and silent divergences between D. miranda and D. affinis, cn is the fraction of completely neutral mutations, and Pa is the proportion of adaptive nonsynonymous mutations.