TABLE 3

The inbreeding load affecting median life span and age-specific mortality estimated on the basis of the data from this and three other experimental studies

LTMedLαLβ
This study0.3890.3070.046
Curtsinger et al. (1992)a0.261−0.0150.029
Hughes (1995)b0.195*0.535*0.045*
0.211**0.209**0.040**
Vermeulen and Bijlsma (2004)c0.4721.7220.003
Mean values0.3060.5520.033
  • All estimates were obtained using D. melanogaster males. For age-specific mortality, the inbreeding load is expressed as an age-independent component (Lα) and as an age-dependent component (Lβ) (see materials and methods).

  • a Estimates are based on four inbred lineages that had undergone 30 generations of full-sib mating (F ≈ 0.99).

  • b Estimates are based on third chromosome homozygotes. Calculations are based on either paired comparisons between homozygous and heterozygous chromosomes (*) or nonpaired comparisons averaged over blocks (**).

  • c Estimates are based on four inbred lineages that had undergone seven generations of full-sib mating (F = 0.785). Calculations are based on survivorship assays carried out at 25°.