TABLE 2

Forelimb defect percentages for backcross fetuses treated on GD 9.25 with 75 mg of RA per kilogram of body weight

Laterality of limb defects (no. of fetuses)
Axiality of paw defects (no. of fetuses)Unilateral
CrossPreaxialPostaxialPre- and postaxialRightLeftBilateral
C57♀ × F1a27.7% (26)b40.4% (38)b30.9% (29)62.8% (59)5.3% (5)31.9% (30)
F1♀ × C57♂67.7% (130)b11.5% (22)b20.8% (40)52.6% (101)8.9% (17)38.5% (74)
  • a One fetus was not included in axiality of paw defects because this fetus had absence of digit 3.

  • b Significantly different between crosses, 2 × 2 χ2 test, P < 0.05.