TABLE 3

Suppression of the heat-shock-driven LIN-3 EGF domain syIs12

StrainHeat shockaVulva cells inducedbnP-valuec
syIs1229°4.97 ± 0.7216
hsf-1(sy441); syIs1229°3.0 ± 016NA
syIs12; cyl-1(sy434)29°4.68 ± 0.82110.3575
syIs12; sup-45(sy509)29°3.0 ± 020NA
syIs1233°5.42 ± 0.6319
hsf-1(sy441); syIs1233°3.0 ± 0 7NA
syIs12; cyl-1(sy434)33°4.61 ± 0.86190.0982*
syIs12; sup-45(sy509)33°4.19 ± 0.7519<0.0001***
  • * Not quite significant;

  • *** extremely significant.

  • a L2 Animals were heat-shocked for 30 min in a water bath at the indicated temperature.

  • b In wild type, three cells are induced.

  • c P-values were calculated using the Mann-Whitney test, comparing the number of cells induced in each double-mutant animal to the number of cells induced in each syIs12 animal.