TABLE 2

Asymptotic and simulated variance of two-dimensional estimators

Variance
intCovarianceCorrelation
Asymptotic
 1,000 sites0.031110.08806−0.01804−0.34
 5,000 sites0.0062230.017612−0.003608−0.34
 10,000 sites0.0031120.008806−0.001804−0.34
 20,000 sites0.0015560.004403−0.000902−0.34
Simulated
 1,000 sites0.0167810.056648−0.00745−0.24
 5,000 sites0.0059660.014237−0.002720−0.3
 10,000 sites0.0023670.007119−0.001810−0.44
 20,000 sites0.0015800.004182−0.001040−0.4
  • Asymptotic variance is obtained from the estimated information matrix as described in the text (Equations 7 and 8). Results are based on a demographic scenario of frec = 5.0, fint = 0.5, and T = 1.0 and a sample size of 50 chromosomes. We assume frec is known and sites are unlinked.