TABLE 1

Su(PDS) mutants

Su(var)3-7 complementationb
MutantMutagenMutationaAmino acid
 changeZygoticMaternalRecessive
 lethalOtherSource
Complementation group 1: Su(var)205
Su(var)205P4EMSC363TQ64nonsenseNDNDNDRL, Su(var)Screen
Su(var)205P5EMSΔNDNDNDRL, Su(var)Screen
Complementation group 2: Su(var)3-7
Su(var)3-7P1P(PZ)0513705137ΔNDRLScreen
Su(var)3-7P2P(PZ)0513705137ΔNDRLScreen
Su(var)3-7P9γ-irridationΔ2610-2622D742frameshift+Su(var)Screen
Su(var)3-7P12P{PZ}CtBP0346Δ2990-3445Δ896D-1020PND+Su(var)Screen
Su(var)3-7P13γ-irridationΔNDRLScreen
Su(var)3-7P25EMSG1971AC529Ys+RLScreen
Su(var)3-7P32P(PZ)0513705137ΔNDRLScreen
Su(var)3-7P43EMSG1632AG416Es+RLScreen
Su(var)3-7P47EMSΔ87AB-88F;89ANDRLScreen
Su(var)3-7P49EMSC2045TQ554nonsense+RLScreen
Su(var)3-7P71EMSG1596AG404Es+RLScreen
Df(3R)126cNDBloomington
Su(var)3-77.1ANDCarol Seum
Su(var)3-79NDCarol Seum
Su(var)3-714NDCarol Seum
Complementation group 3
Su(PDS)P80EMSUnknown+++RLScreen
Complementation group 4
Su(PDS)P86EMSUnknown+++RL, Su(var)Screen
  • a The numerical designations are based on sequences found in GenBank. The GenBank accession number for the Su(var)205 sequence is M57574.1 and for the Su(var)3-7 sequence is X52187.1. Δ indicates the mutation is a deletion.

  • b Testing whether mutants can complement zygotic, maternal, or recessive lethal phenotypes associated with mutations. See results for a description of the crosses. Minus indicates the alleles fail to complement; plus indicates the alleles complement.

  • ND, not done; RL, recessive lethal; s, semilethal—the allele combination does not fully complement and most (>95%) flies with this combination do not develop into adults.