TABLE 5

McDonald-Kreitman tests

GeneDSPSDNPNN.I.P-value
sryδ1516 810.120.021
sryα1810 374.20.060
sryβ1213 410.230.176
janA 515 310.110.059
janB1111 700.000.026
ocn 610 200.000.183
All677531100.290.001
janA-ocna 836 610.04<0.001
• a Mutations were polarized to the D. simulans lineage using the D. yakuba sequence as an outgroup.

• DS, number of fixed synonymous substitutions; PS, number of polymorphic synonymous substitutions; DN, number of fixed nonsynonymous substitutions; PN, number of polymorphic nonsynonymous substitutions; N.I., neutrality index (Rand and Kann 1996). P-values were calculated by a G-test except for janB and ocn, which were calculated by Fisher's exact test.