TABLE 5

Reconstruction results of the conditional enumeration method for the 330-member pedigrees and the 546-member pedigrees with different marker allele frequencies and distances between adjacent markers

N (type)aLbcMcFreqdλSize of
 SACHC*Ratio of
 likelihoods of
 2 SACHC*eTotal probability of
 50/100/500/1000 top
 configurations (%)fTime
 (hr:min:sec)
330 (SNP)100.50.50.9656493.7/—/—/— 0:00:02
0.9952561.04589.7/98.3/—/— 0:00:09
0.99640,9601.01588.3/96.8/99.9/99.99 0:23:25
330 (SNP)101.00.50.9656499.4/—/—/— 0:00:02
0.9901,0241.08892.6/97.6/99.9/99.99 0:00:36
0.995327,6801.04288.9/94.1/99.4/99.8 3:03:19
330 (SNP)101.00.90.8501,024 7.8/15.6/78.1/99.1 0:00:51
0.9302,0481.080 7.2/14.5/72.3/91.7 0:01:27
0.96516,3841.190 6.1/12.2/60.8/77.1 0:10:00
330 (SNP)103.00.50.8502,04848.5/63.6/96.0/99.4 0:01:46
0.93032,7681.60530.2/41.2/71.3/82.7 0:22:32
0.965589,8241.59919.1/26.7/50.3/61.5 6:01:52
546 (SNP)401.00.50.94076853.3/70.2/98.5/— 0:01:36
0.96512,2881.17045.6/60.1/87.8/94.7 0:24:33
0.975147,4561.07942.3/55.6/82.1/89.8 4:50:10
546 (Mic)401.00.10.9751 0:00:01
0.9851281.14999.9/1.0/—/— 0:00:23
0.991524,2881.12698.1/98.9/99.9/99.9924:35:49
  • a N denotes the number of individuals in the pedigree, and type denotes the marker type, where SNP (Mic) denotes SNP (microsatellite) markers.

  • b Number of linked marker loci.

  • c Distance between adjacent markers.

  • d Allele frequency. For the microsatellite markers, each allele has the frequency 0.1.

  • e The ratio of the sums of the likelihoods of all configurations in two different SACHC* corresponding to two different λ values (current row over previous row).

  • f Sum of likelihoods of top configurations over sum of likelihoods of all configurations in SACHC*; top configurations are those with highest likelihood in SACHC*.