TABLE 2

Summary statistics for 15 X-linked loci in worldwide samples

LocusBase pairsNSθ (%)π (%)TDFLDFWHD (%)aTMRCAbFSTReference
APXL 4,63841190.0960.080−0.541−1.1700.1241.39 8400.226This study
AMELX 5,33141170.0750.061−0.601−1.759−0.2820.801,1780.343This study
TNFSF5 5,23941160.0710.035−1.634−1.488−4.987*0.641,3400.062This study
RRM2P4 2,38541130.1270.119−0.2060.548−3.5770.891,7140.079This study
ALAS2 4,74241 70.0350.015−1.527*−1.8730.6590.55 6560.305Nachman et al. (2004)
MSN 4,57641 90.0460.035−0.662−1.956−2.0460.91 6050.636Nachman et al. (2004)
Dmd44 2,95941190.1500.143−0.160−0.332−2.7340.931,9380.043Nachman and Crowell (2000)
Dmd7 2,38341 90.0880.034−1.778*−3.306*−0.9051.83 5760.275Nachman and Crowell (2000)
L1CAM 2,08741 60.0670.018−1.925*−2.264*0.3711.07 7620.061Saunders et al. (2002)
G6PD 2,91841100.0800.039−1.512−1.0480.2931.32 6920.296Saunders et al. (2002)
PDHA1 4,06935240.1430.1800.8860.916−2.7630.981,7440.609Harris and Hey (1999)
FIX 3,72836 60.0390.014−1.713*−1.3270.5081.00 4700.013Harris and Hey (2001)
MAO-A18,82056390.0380.0430.429−0.522−8.3451.01 4490.125Gilad et al. (2002)
P2Y1010,16369330.0680.033−1.633−3.073*−3.2190.91 8980.061Kaessmann et al. (1999)
DACH210,21562440.0920.072−0.731−2.738*−2.0240.921,2010.006Yu et al. (2002b)
Average 5,61745180.0810.061−0.887−1.472−1.9261.011,0040.209
  • * Two-tailed P ≤ 0.025 in Monte Carlo simluation.

  • a Human-chimpanzee sequence divergence.

  • b TMRCA values are based on Watterson's (1975) estimator of 3Neμ and are in units of 1000 years (KYA).

  • Only SNPs were included in all analyses except the H test where indels were also used. Underlined loci were sequenced in same panel of 41 men.