Experiment 1 | Experiment 2 | Experiment 3 | ||||
---|---|---|---|---|---|---|

Mutational statistics for the quasi-normal lines | All nonlethals | Mutational statistics for the quasi-normal lines | All nonlethals | Mutational statistics for the quasi-normal lines | All nonlethals | |

b_{M} (×10^{3}) | −2.08 ± 1.77 | −4.88 ± 1.87 | −5.68 ± 0.857 | −7.65 ± 0.873 | −4.01 ± 1.20 | −3.79 ± 1.44 |

b_{C} (×10^{3}) | −4.12 ± 5.19 | −5.33 ± 1.62 | −0.730 ± 2.45 | |||

DM (×10^{3}) | 1.06 (−2.15/4.48) | 2.86 (0.10/9.72) | 6.66 (5.16/8.25) | 8.42 (6.42/10.5) | 3.75 (1.60/6.43) | 3.27 (0.89/6.35) |

u* (×10^{2}) | 0.25 (−0.88/3.45) | 2.86 (−1.57/12.2) | 24.1 (10.9/44.6) | 8.12 (4.68/12.4) | 5.89 (−0.34/16.7) | 11.2 (−2.01/37.8) |

s* | −1.27 (−3.56/−0.181) | 0.205 (−0.022/0.764) | 0.023 (0.010/0.035) | 0.100 (0.069/0.133) | 0.064 (0.021/0.165) | 0.064 (−0.003/0.215) |

*b*_{M}and*b*_{C}are the regression coefficients on assay generation (with standard errors) of the genotypic means and control means for each generation, respectively. The estimates of DM,*u**, and*s** (after normalizing the data by the mean control genotypic values) are the means over 1000 bootstrap replicates, with corrections for bias.