TABLE 4

Amount and distribution of polymorphisms at Msn and Alas2 by geographic region

LocusGeographic regionSample sizeSaπ (SD) (%)aθ (SD) (%)aTajima's DbFu and Li's DbFay and Wu's Hb
Msn Africa1040.035 (0.006)0.031 (0.019)0.500.350.36
Non-Africa3180.014 (0.006)0.044 (0.020)–1.93***–2.68***–2.99**
Europe1030.013 (0.010)0.023 (0.015)–1.39**0.06–3.02**
Asia1100.000 (0.000)0.000 (0.000)
Americas1070.031 (0.013)0.054 (0.029)–1.65***–1.42*–2.31*
Alas2 Africa1060.044 (0.006)0.042 (0.025)0.23–0.300.80
Non-Africa3110.001 (0.001)0.005 (0.005)–1.40**–2.32**0.12
Europe1010.004 (0.003)0.008 (0.008)–1.24*–1.69**0.36
Asia1100.000 (0.000)0.000 (0.000)
Americas1000.000 (0.000)0.000 (0.000)
Msn-Alas2 Africa10100.040 (0.005)0.038 (0.019)0.37–0.041.16
Non-Africa3190.008 (0.003)0.024 (0.011)–2.05***–3.17***–2.87*
Europe1040.009 (0.005)0.015 (0.009)–1.56**–0.88–2.67**
Asia1100.000 (0.000)0.000 (0.000)
Americas1070.015 (0.007)0.027 (0.014)–1.65***–1.42*–2.31*
  • * P < 0.10

  • ** P < 0.05

  • *** P < 0.01.

  • a Polymorphism statistics are based on single-nucleotide polymorphisms only and do not include indels.

  • b Measures of the frequency distribution of segregating variation are based on both SNPs and indels; values based on SNPs alone are very similar and do not change significance levels for any of the tests.