TABLE 5

Influence of mutants from homologous recombination on the mph1 forward mutator phenotype to canavanine resistance

StrainMutation rate × 107Relative rateStrainMutation rate × 107Relative rate
Wild type3.0 ± 0.4311mph125.5 ± 2.918.5
4.2 ± 0.56227.8 ± 3.026.6
4.0 ± 0.60321.2 ± 2.735.3
2.9 ± 0.44430.1 ± 3.6410.4
3.6 ± 0.50524.4 ± 2.756.7
4.2 ± 0.57629.5 ± 3.367.0
1.0 ± 0.1774.6 ± 0.6274.6
rad5128.3 ± 3.319.4rad5230.8 ± 4.137.7
41.6 ± 4.529.944.3 ± 5.5415.3
rad51 mph130.8 ± 3.6110.336.3 ± 4.2510.1
37.4 ± 4.128.937.6 ± 4.468.9
rad5530.5 ± 3.437.65.5 ± 0.8075.5
rad55 mph130.9 ± 3.537.7rad52 mph118.4 ± 2.534.6
37.9 ± 4.7413.1
34.2 ± 4.159.5
44.4 ± 5.2610.5
7.2 ± 1.077.2
  • Relative rates were calculated by normalizing mutant mutation rates to the wild-type rate determined in that particular experiment, which is indicated by the indices 1–7. The errors indicated are the quotients of the standard deviations of the number of mutations (Lea and Coulson 1948) and total cell numbers.