TABLE 1

Parameters for mutations affecting fitness correlates

StrainMethodUaEmbedded Image
Productivity
msh-2 B-M0.249–0.2110.0168 (0.0047)
Boot0.274 (0.496, 0.144)–0.106 (–0.062, –0.155)
MLC0.383 (0.696, 0.158)–0.160 (–0.100, –0.342)
N2B-M0.049 (0.024)–0.088 (0.032)0.0008 (0.0003)
MLC0.018 (0.010, 0.037)–0.369 (–0.446, –0.305)
r
msh-2 B-M0.081–0.4160.0213 (0.0071)
Boot0.090 (0.178, 0.036)–0.211 (–0.121, –0.322)
MLC0.069 (0.145, 0.044)–0.529 (–0.281, –0.528)
N2B-M0.014 (0.006)–0.222 (0.060)0.0033 (0.0008)
MLV0.024 (0.012, 0.259)–0.131 (–0.219, –0.033)
Survival
msh-2 B-M0.051–0.4580.0127 (0.0051)
Boot0.058 (0.124, 0.018)–0.232 (–0.115, –0.386)
N2B-M0.003 (0.001)–0.390 (0.084)0.0031 (0.0007)

Estimates of the per generation genomic mutation rate (U), average mutational effect (a), and mutational heritability Embedded Image for each trait for the N = 1 population-size treatment in the 20-generation experiment compared to those for the natural MA lines (N2) are shown. B-M point estimates, bootstrapped B-M estimates (Boot), and ML estimates (MLC and MLV are for constant and variable-effects models, respectively) of U and a are also shown. B-M and ML (averaged across five assays) estimates for the natural MA lines (N2) are taken from Vassilieva et al. (2000, Tables 3 and 4). Only estimates from the ML model that provided the best fit are listed for the natural MA lines. One standard error or 95% confidence intervals are shown in parentheses following each estimate.