TABLE 1

Effect of the modifiers on pteridine eye-pigment levels

ModifierClassScreen
effecta
nbwD; Prat:bw st/stbt-test
P valuec
Screen
effecta
nbwD; P[ry+; bw+] st/stbt-test
P valuec
Control100.079 ± 0.003100.137 ± 0.005
Mod-1-11ss100.047 ± 0.00610-9ss100.077 ± 0.00510-15
Mod-1-21ss100.057 ± 0.00710-6ne100.114 ± 0.00710-7
Mod-1-31ss100.060 ± 0.00410-8ws100.098 ± 0.01410-6
Control100.067 ± 0.003100.133 ± 0.008
Mod-1-41ss100.038 ± 0.00510-9ss100.070 ± 0.00210-10
Control100.067 ± 0.004100.135 ± 0.005
Mod-1-51ss100.031 ± 0.00410-13ss100.043 ± 0.00210-17
Control100.070 ± 0.005100.136 ± 0.010
Mod-2-11ss100.040 ± 0.005710-10ss100.082 ± 0.008310-10
Mod-2-21ss90.040 ± 0.009610-5ss100.088 ± 0.009610-9
Mod-2-52se90.100 ± 0.01110-6we100.190 ± 0.008710-10
Control100.068 ± 0.005100.130 ± 0.010
Mod-2-34ws100.050 ± 0.00210-7ne100.146 ± 0.0090.001
Mod-2-41ss90.049 ± 0.00310-8ne100.114 ± 0.0080.0006
Control100.069 ± 0.006100.122 ± 0.013
Mod-3-61ws100.057 ± 0.0050.00035ne90.112 ± 0.0080.05
Mod-3-23ws100.066 ± 0.0060.37ne80.132 ± 0.0100.10
Mod-3-103ws80.070 ± 0.0070.78ne90.126 ± 0.0090.53
Mod-3-71ss100.058 ± 0.00030.0003ss100.070 ± 0.00710-7
Control100.063 ± 0.004100.136 ± 0.009
Mod-3-12se70.075 ± 0.0076 × 10-3ne70.155 ± 0.0100.002
Mod-3-113ss70.059 ± 0.0040.07ss80.140 ± 0.0080.32
Mod-3-93ws100.063 ± 0.0050.99ne80.135 ± 0.0100.80
Control100.072 ± 0.004100.139 ± 0.007
Mod-3-31ws90.057 ± 0.0061.4 × 10-4ws80.121 ± 0.013 × 10-4
Mod-3-44ws90.080 ± 0.0060.0071ss80.107 ± 0.0052 × 10-8
Mod-3-51ss70.058 ± 0.00410-5ne70.128 ± 0.0036 × 10-4
Control100.069 ± 0.004100.123 ± 0.009
Mod-3-83ss70.063 ± 0.0090.175ne100.125 ± 0.0050.55
Mod-3-123ws90.064 ± 0.0040.043ne70.121 ± 0.0190.80
Control100.057 ± 0.004100.148 ± 0.009
Mod-Y-11ss100.033 ± 0.00410-9ss100.112 ± 0.00710-9
  • ss, strong suppressor; ne, no effect; ws, weak suppressor; se, strong enhancer; we, weak enhancer.

  • a The effect of the modifiers on eye color was observed for both transgenes on 0- to 4-hr-old young adult fly heads.

  • b Pigment values are expressed as mean absorbance at 480 nm ± standard deviation values obtained for n assays.

  • c The effect of the modifier on pigment levels was determined by performing a t-test. The P value represents the significance of the difference between the pigment value with and without the modifier at 95% confidence. Sets of modifier genotypes are grouped with their control genotype.