TABLE 3

Posterior distribution statistics: incomplete association

Parametersc
PedigreeaReplicateAnalysisbaedeEmbedded Image Position (M)t
Simple1LDL1.03 (0.10)-0.07 (0.17)0.87 (0.07)0.161 (0.053)81 (12)
L1.04 (0.10)0.00 (0.15)0.86 (0.07)0.118 (0.073)
2LDL1.03 (0.11)-0.08 (0.18)0.87 (0.07)0.172 (0.039)82 (15)
L1.04 (0.10)-0.01 (0.16)0.86 (0.07)0.143 (0.059)
3LDL1.03 (0.11)-0.07 (0.18)0.87 (0.07)0.177 (0.030)75 (17)
L1.04 (0.10)-0.01 (0.11)0.86 (0.07)0.171 (0.048)
Complex1LDL0.78 (0.08)0.09 (0.11)1.10 (0.08)0.182 (0.015)93 (20)
L0.78 (0.09)0.10 (0.13)1.10 (0.08)0.188 (0.021)
2LDL0.87 (0.15)0.10 (0.23)1.15 (0.10)0.183 (0.034)80 (13)
L0.89 (0.16)0.16 (0.22)1.13 (0.10)0.195 (0.035)
3LDL0.99 (0.08)-0.01 (0.10)1.02 (0.07)0.192 (0.030)130 (20)
L1.01 (0.08)0.03 (0.11)1.01 (0.07)0.156 (0.040)
  • Initially, 43% of haplotypes with SNP allele 1 carried the QTL mutant allele.

  • a Simple pedigree population consists of independent full-sib families; complex population is a four-genera- tion pedigree with random mating.

  • b LDL analysis combines both linkage disequilibrium and pedigree information; L analysis uses only linkage.

  • c Mean of the posterior distribution (SD of the posterior distribution).