TABLE 2

Posterior distribution statistics: complete association

Parametersc
PedigreeaReplicateAnalysisbaedeEmbedded Image Position (M)t
Simple1LDL1.06 (0.08)0.02 (0.10)0.96 (0.07)0.169 (0.031)73 (14)
L1.00 (0.09)-0.05 (0.13)1.00 (0.07)0.148 (0.044)
2LDL1.07 (0.08)0.08 (0.13)0.99 (0.07)0.183 (0.027)79 (20)
L1.07 (0.10)0.14 (0.15)0.99 (0.08)0.144 (0.062)
3LDL1.08 (0.10)0.08 (0.10)0.88 (0.07)0.180 (0.014)90 (18)
L1.02 (0.11)-0.01 (0.12)0.92 (0.08)0.192 (0.028)
Complex1LDL0.94 (0.08)-0.05 (0.09)1.13 (0.08)0.182 (0.024)71 (16)
L0.88 (0.09)0.01 (0.10)1.18 (0.09)0.197 (0.033)
2LDL0.99 (0.08)-0.01 (0.10)1.03 (0.07)0.187 (0.020)101 (21)
L0.95 (0.09)0.01 (0.12)1.07 (0.08)0.168 (0.042)
3LDL0.96 (0.08)0.05 (0.09)1.09 (0.08)0.169 (0.017)141 (15)
L0.91 (0.09)0.05 (0.10)1.11 (0.08)0.160 (0.031)
  • All haplotypes with SNP allele 2 carried the QTL mutant allele.

  • a Simple pedigree populations consist of independent full-sib families; complex population is a four-genera- tion pedigree with random mating.

  • b LDL analysis combines both linkage disequilibrium and pedigree information; L analysis uses only linkage.

  • c Mean of the marginal posterior distribution (SD of the marginal posterior distribution).