TABLE 6

Maternal rescue of synMuv phenotype

Penetrance of the Muv phenotype in animals of a/a; b/b genotype descended from animals of maternal genotype (%)
Class A mutationClass B mutationa/+; b/+a/+; b/ba/a; b/+a/a; b/bb
lin-8(n111) lin-9(n112) 72 (n = 57)a83 (n = 141)a100 (n = 183)100 (n = 165)
lin-8(n111) lin-35(n745) 45 (n = 65)aND97 (n = 149)100 (n = 209)
lin-8(n111) lin-36(n766) 14 (n = 93)a23 (n = 216)a84 (n = 300)98 (n = 207)
lin-8(n111) lin-37(n758) 31 (n = 69)a98 (n = 133)a85 (n = 188)100 (n = 161)
lin-15(n433) lin-54(n2231) 9 (n = 89)aND21 (n = 211)99 (n = 164)
lin-15(n767) lin-13(n770) 58 (n = 64)a97 (n = 238)a90 (n = 220)95 (n = 230)
lin-15(n767) lin-52(n771) 83 (n = 98)a103 (n = 225)a90 (n = 294)100 (n = 211)
lin-15(n767) lin-53(n833) 103 (n = 76)aND100 (n = 64)100 (n = 116)
lin-15(n433) dpl-1(n2994) 11 (n = 95)a75 (n = 125)a50 (n = 298)78 (n = 234)
lin-38(n751) lin-9(n112) 81 (n = 65)a100 (n = 146)99 (n = 189)a100 (n = 165)
lin-56(n2728) lin-15(n744) 93 (n = 92)a99 (n = 200)ND100 (n = 163)

The contribution of class A and class B genes to the maternal rescue of the synMuv phenotype of doubly homozygous animals descended from either singly or doubly heterozygous mothers was determined by counting the number of Muv animals of phenotype R, where R is the phenotype produced by the cis marker r. Doubly heterozygous mothers were obtained by mating N2 males with marked doubly homozygous hermaphrodites. Singly heterozygous mothers were obtained by mating males homozygous for one of the synMuv mutations with marked doubly homozygous hermaphrodites. A strain homozygous for lin-35 was obtained by the general procedure used for the isolation of strains homozygous for single synMuv mutations. dpy-14 was used to balance lin-35. The lin-8; lin-9 strain was marked with lon-1. The lin-35; lin-8 strain was marked with unc-13. The lin-8; lin-36 strain was marked with unc-32. The lin-8; lin-37 strain was marked with lon-1. The lin-38; lin-9 strain was marked with unc-52. The lin-13; lin-15(n767) strain was marked with unc-93 or unc-32. The lin-52; lin-15(n767) strain was marked with sma-3. The lin-53; lin-15(n767) strain was marked with dpy-5 or lin-11. The lin-54; lin-15(n433) strain was marked with dpy-20. The dpl-1; lin-15(n433) strain was marked with rol-6. The lin-56; lin-15(n744) strain was marked with rol-6. ND, not determined.

  • a These data were obtained by estimating the penetrance and by assuming that the number of doubly homozygous animals were one-quarter of the R progeny.

  • b These data are from Table 1 of Ferguson and Horvitz (1989).