TABLE 4

Hemocytes in Toll pathway and mxc mutants

GenotypeNHemocytes
cells/ml (106)b
Plasmatocytes (%)Podocytes (%)Lamellocytes (%)
TM3/+a101.3 ± 0.6100<0.1<0.1
Tl10b/+123.1 ± 2.182.24.013.8
cactA2/CyO y+a101.7 ± 0.7990.20.8
cactA2/cactA2105.1 ± 1.581.91.117.0
Binsn/Y;TM6c/Tla102.5 ± 1.1>99<0.1<0.1
Binsn/Y;TlRXA/Tlr632111.7 ± 0.899.50.4<0.1
y1 mxcG43/Y;TM6c/Tl116.4 ± 2.9*95.22.82.0
y1 mxcG43/Y;TlRXA/Tlr63293.2 ± 1.9**95.33.01.7
Binsn/Y;TM6c/tub238a141.3 ± 1.0>990.2<0.1
Binsn/Y;tub283/tub238131.0 ± 0.7>990.3<0.1
y1 mxcG43/Y;TM6c/tub238104.5 ± 1.4*90.4***6.9***2.7***
y1 mxcG43/Y;tub283/tub238101.0 ± 0.3**>97***1.1***1.8***
  • Effects of loss of Toll were evaluated among progeny of y1 mxcG43/Binsn;TlRXA/TM6c females and Binsn/Y;TM6c/Tlr632 males. Effects of loss of tube were evaluated among progeny of y1 mxcG43/Binsn;tub238/TM6c females crossed to Binsn/Y;tub238/TM6c males. *P < 0.01; significantly different from Binsn/Y control. **P < 0.01; significantly different from internal mxcG43 control category in this experiment. ***P < 0.01; cell type distribution significantly different from Binsn/Y.

  • a Genotype of sibling larvae, which served as internal controls in this experimental series. N, no. of animals used for this genotype.

  • b Mean hemocyte density per milliliter of hemolymph ± SE.