TABLE 2

Enhancement of weak inturned and fuzzy phenotypes by mutations in frizzled and other upstream genes

SampleGenotypeTemp.Fraction of mhcaSignificant difference fromb
1inII5325°0.13 (0.06)
2pk125°0.01 (0.01)
3dsh125°0.01 (0.07)
4JzR5325°0.01 (0.01)
5dsh1; inII5325°0.55 (0.07)1,3
6pk1; inII5325°0.64 (0.07)1, 2
7fzR53 inII5325°0.54 (0.09)1, 4
8inII53/Df25°0.34 (0.12)
9VangrBS4225°0.35 (0.06)
10VangTBS42; mII53/Df25°0.76 (0.08)8, 9
11inHC31/Df25°0.19 (0.05)
12stan325°0.03 (0.005)
13stan3; inHC31/Df25°0.72 (0.13)11, 12
14inII5318°0.013 (0.01)
15fzHD2118°0.01 (0.02)
16fzHD21 inII5318°0.62 (0.02)14, 15
17ff1125°0.002 (0.004)
18fyIN11;fzR5325°0.15 (0.02)4, 17
19fyN12/fy225°0.34 (0.10)
20JZr52/JZK2125°0.02 (0.01)
21fyJN12/fy2; fzR52/fzK2125°0.71 (0.07)19, 20
22fyIN1225°0.04 (0.04)
23fyIN12;fzR5325°0.42 (0.07)4, 22
  • a The fraction of multiple hair cells was scored in a 20 × 5 cell box in the C region of the wing just anterior to the posterior cross vein. The standard deviation is given in parentheses. We have used this region previously (Wong and Adler 1993). Six to 12 wings were scored for each genotype.

  • b A t-test was used to compare samples. All significant differences had P values of <0.001.