TABLE 3

The MapManager QT analysis of the lesion and log-lesion data from the confirmatory cross 2

Chromosome markerPhenotypeGenderLOD% varianceP valueSignificanceModel with respect to C57BL/6J allele
D1MIT359LesionM + F3.370.00049SuggestiveAdditive
D1Mit50Total chol.M + F7.6182.5E-08Highly sig.Additive
D1Mit50Total chol.M5.9261.4E-06Sig.Additive
D1Mit50Non-HDLM + F7.0171.1E-07Highly sig.Additive
D1Mit50Non HDLM5.4244.0E-06Highly sig.Additive
D1Mit50HDLM + F5.2127.0E-06Highly sig.Additive
D1Mit50HDLM2.7111.93E-03SuggestiveAdditive
D1Mit50HDLF4.1188.4E-05Sig.Additive
D10MIT49LesionM8.8371.6E-09Highly sig.Dominant/additive
D10MIT214LesionM + F11.9251.3E-12Highly sig.Dominant/additive
D10MIT214LesionM5.8241.5E-06Highly sig.Dominant/additive
D10MIT214LesionF6.8271.5E-07Highly sig.Dominant/additive
D14MIT63LesionM + F2.660.00245SuggestiveDominant
D14MIT63LesionM3.1130.00076SuggestiveDominant
D14MIT158LesionM3.3140.00047SuggestiveDominant
  • Chol., cholesterol; Sig., significant.