Nucleotide substitutions accumulated during the high-temperature adaptation of ϕX174
| Mutation | Gene | AA change | First detected | Final status |
|---|---|---|---|---|
| 1727 C → T | F242 | L → F | 4 | Fixed |
| 1614 C → A | F204 | T → N | 8 | Fixed |
| 927 G → T | J27 | G → V | 20 | Polymorphic |
| 926 G → T | J27 | G → C | 28 | Polymorphic |
| 2903 G → T | G170 | C → F | 4 | Lost |