HKA test for difference in distribution of nonsynonymous substitutions between DR/HV1/HV2 and the rest of the S domain in a comparison between SRK2 alleles vs. a comparison between the SRK2 alleles and SLGB2

Rest of the S domainaDR, HV1, HV2
Within-haplotype polymorphism data
Segregating sites (obs)120
Segregating sites (exp)8.773.23
Total no. of sites1112183
Between-gene divergence
No. differences (obs)77
No. differences (exp)10.233.77
Total no. of sites1106189
χ2 = 4.715P = 0.0299
  • Sample size was eight.

  • a The regions analyzed corresponded to the regions indicated by the shaded bars in Figure 5a.