TABLE 1

Comparison of composite interval mapping results in RC and RR simulations

RCRR
Heritability = 0.3, markers every 5 cM, equal distribution of QTL effects
Total QTL14.7 ± 0.5 (5–28)17.9 ± 0.4 (11–26)
X chromosome QTL2.7 ± 0.2 (0–10)4.1 ± 0.2 (1–9)
Chromosome 2 QTL5.1 ± 0.2 (1–13)6.8 ± 0.3 (3–17)
Chromosome 3 QTL6.9 ± 0.3 (2–16)7.0 ± 0.3 (2–14)
No X QTL10/1000/100
QTL on both 2 and 3 bigger than X86/10040/100
Largest QTL on X3/10023/100
Largest QTL near centromere46/10014/100
Heritability = 0.3, markers every 5 cM, exponential distribution of QTL effects
Total QTL15.1 ± 0.5 (8–34)17.1 ± 0.4 (10–27)
X chromosome QTL2.8 ± 0.2 (0–10)4.3 ± 0.2 (0–10)
Chromosome 2 QTL6.2 ± 0.3 (1–15)6.5 ± 0.3 (2–14)
Chromosome 3 QTL6.1 ± 0.3 (2–15)6.4 ± 0.3 (2–15)
No X QTL11/1001/100
QTL on both 2 and 3 bigger than X85/10047/100
Largest QTL on X3/10027/100
Largest QTL near centromere46/1008/100
Heritability = 0.7, markers every 5 cM, equal distribution of QTL effects
Total QTL30.0 ± 0.5 (18–41)32.1 ± 0.4 (24–45)
X chromosome QTL6.6 ± 0.2 (2–13)7.9 ± 0.2 (3–13)
Chromosome 2 QTL12.0 ± 0.3 (5–19)11.9 ± 0.3 (6–19)
Chromosome 3 QTL11.4 ± 0.3 (3–20)12.3 ± 0.3 (6–18)
QTL on both 2 and 3 bigger than X89/10042/100
Largest QTL on X2/10033/100
Largest QTL near centromere53/10013/100
Heritability = 0.3, markers every 1 cM, equal distribution of QTL effects
Total QTL28.5 ± 0.8 (12–48)32.9 ± 0.9 (13–57)
X Chromosome QTL5.6 ± 0.4 (0–22)8.0 ± 0.4 (3–20)
Chromosome 2 QTL10.9 ± 0.5 (3–27)12.3 ± 0.6 (1–29)
Chromosome 3 QTL11.5 ± 0.5 (3–29)12.6 ± 0.6 (4–29)
No X QTL6/1000/100
QTL on both 2 and 3 bigger than X77/10036/100
Largest QTL on X1/10030/100
Largest QTL near centromere52/10010/100
  • Means ± standard errors or counts are given with the ranges presented parenthetically. In addition to numbers of predicted QTL, we evaluated how often the predicted QTL of largest effect size on both major autosomes was associated with more of the phenotypic variance than the QTL of largest size on the X chromosome. We also note how often the predicted QTL of largest effect was within 5 cM of the centromere of one of the two major autosomes.