TABLE 1

Naive vs. polygenic model simulation

TheoreticalEstimated
QTLPolygeneModelaLocationAdditiveDominantPolygenic
05N _ b 1.79 (0.85)–0.99 (1.10) _ c
P b –0.036 (1.06)0.088 (1.41)4.29 (0.96)
010N b 3.75 (1.10)–1.70 (1.26) c
P b 0.23 (1.27)– 0.03 (1.67)8.59 (0.91)
50N29.02 (6.05)5.03 (0.83)0.12 (0.86) c
P29.84 (4.73)5.02 (0.88)0.14 (0.92)0.07 (0.89)
55N29.93 (5.13)6.6 (0.61)–0.75 (0.91) c
P29.42 (5.07)4.97 (0.70)0.03 (0.96)4.45 (0.84)
510N29.76 (5.85)8.16 (0.77)–1.41 (1.25) c
P29.60 (5.78)4.94 (0.97)0.04 (1.25)8.82 (0.98)

The values in parentheses are the standard deviations from 100 simulations. The numbers in the first two columns are the theoretical QTL and polygenic effects.

  • a N and P stand for the naive model and our polygenic model, respectively.

  • b The QTL position is not estimated since most of the maxd{2 LR(d)}'s are not significant among 100 simulations.

  • c The polygenic effect is nonestimable in the naive model.