TABLE 1

Single-locus full-sibship likelihoods

Full-sib genotypesSibship likelihood
AA Embedded Image
AB Embedded Image
AA BB Embedded Image
AA AB Embedded Image
AA AB BB Embedded Image
AA BC Embedded Image
ABAC Embedded Image
AA AB AC Embedded Image
AA AB BC Embedded Image
AB AC BC 8pApBpC(1 – pX)(1/4)n
AA AB AC BC Embedded Image
AC BD 8pApBpCpD(1/4)n
AD AC BC 8pApBpCpD(1/4)n
AC AD BC BD 8pApBpCpD(1/4)n

nAB is number of individuals with genotype AB; n is total number of individuals in the full sibship; pX is the probability of all unspecified alleles. For example, for the family consisting of nAA individuals with genotype AA, pX = 1 – pA, and for the second last full-sib genotype configuration listed (AB, AC), pX = 1 – pA pB pC.