TABLE 5

Mutational parameters for second chromosome Mukai-type viability (Embedded Image )

GenerationΔM × 102ΔV × 103λc
(lower bound)
E(s)c
(upper bound)
hws2
250a0.046 ± 0.013***0.051 ± 0.0380.0041 ± 0.00880.111 ± 0.0890.117 ± 0.205d
255a0.140 ± 0.023***0.087 ± 0.029***0.0226 ± 0.01060.062 ± 0.0230.351 ± 0.165*
Joint analysisa0.093 ± 0.014***0.029 ± 0.0200.0297 ± 0.04360.031 ± 0.0220.037 ± 0.577
Joint analysisb0.090 ± 0.016***0.025 ± 0.0130.0315 ± 0.02350.0285 ± 0.0150.243 ± 0.548
  • See text for further explanation. *P < 0.05; ***P < 0.001 (one-tailed tests).

  • a ln(number of wild progeny/number of Cy progeny).

  • b Number of wild progeny/number of Cy progeny.

  • c Since the distributions of λ and E(s) estimates are unknown, significance tests were not performed.

  • d For mutations accumulated in the control.