TABLE 3

Mutational parameters for second chromosome viability (Embedded Image )

GenerationΔM × 102ΔV × 103λa
(lower bound)
E(s)a
(upper bound)
hws2
2500.043 ± 0.016**0.112 ± 0.052***0.0017 ± 0.00160.257 ± 0.1620.270 ± 0.252b
2550.151 ± 0.030***0.130 ± 0.047***0.0177 ± 0.00980.085 ± 0.0360.328 ± 0.187*
Joint analysis0.094 ± 0.018***0.076 ± 0.032**0.0116 ± 0.00720.081 ± 0.0370.323 ± 0.363
  • See text for further explanation. Embedded Image = ln(number of wild progeny/number of Cy/L2 progeny). *P < 0.05; **P < 0.005; ***P < 0.001 (one-tailed tests).

  • a Since the distributions of λ and E(s) estimates are unknown, significance tests were not performed.

  • b For the pool of mutant copies in the control population.