TABLE 1

Expansions and contractions with the pFP59 donor template

% rearranged in recipient only% rearranged
in donor
only
% rearranged
in both
TotalExpansionsContractionsDonoraRecipienta
WT15.9015.902.9NR: 67NR: 56
(11/69)(0/69)(11/69)(0/69)(2/69)BR: 1 (-1/NR);
1 (-1)
R: 3 (-2); 8 (-1)
BR: 2 (-1)
WTNA0.6NANR: 175NA
    (non-induced)(1/176)R: 1 (+1)
rad1001.4NR: 71NR: 71
(0/72)(0/72)(1/72)BR: 1 (+3)BR: 1 (+3)
msh22.42.4000NR: 126NR: 123
(3/126)(3/126)(0/126)(0/126)(0/126)R: 1 (+1);
2 (+1/NR)
msh611.7011.700NR: 60NR: 53
(7/60)(0/60)(7/60)(0/60)(0/60)R: 1 (-4);
6 (-1)
pms110.03.36.71.70NR: 59NR: 54
(6/60)(2/60)(4/60)(1/60)(0/60)R: 1 (-1/NR)R: 1 (-2):
3 (-1);
1 (+1); 1 (+4)
  • a NR, nonrearranged; R, rearranged only in donor (second column), or only in recipient (third column); BR, both donor and recipient rearranged. The number of events of each kind is followed by the kind of event: for examples, 2 (-2) stands for 2 contractions removing two 36-bp units; 1 (+3/NR), in the same survivor colonies, we found two kinds of repeated arrays, one with an expansion (+3) and one that has not been rearranged. NA, there is no recipient in this experiment.