TABLE 5

Results from model fitting for data in Table 1, using NOD.B6Idd10R2 strain

Model fitted
Fitted penetrances for
Idd3/Idd10
PenetranceLog oddsLiability:
GenAddHetMulAddHetMulAdd
NNNN0.760.750.670.800.790.640.510.79
NNNB0.630.600.580.600.620.580.640.62
NNBB0.490.520.550.480.490.540.510.49
NBNN0.580.540.530.540.570.530.490.57
NBNB0.360.390.400.410.370.390.360.37
NBBB
BBNN0.220.270.290.170.210.270.220.22
BBNB
BBBB0.050.040.040.100.060.040.060.06
Difference in -2 ln L3.5311.086.890.6110.0022.390.45
P value for rejection
    Asymptotic0.170.0040.030.740.0071 × 10-50.80
    Empirical0.190.0060.040.750.0061 × 10-40.79