TABLE 2

Gene-trap lines in which the trapped genes are identified molecularly

StrainGeneViability of homozygotesChromosomal locationCorresponding genomic clones or STSsMechanism of Gal 4 expressionHomologous ESTs in flyHomologs in other organisms
GTlpokanterior open (aop)Lethal22DBACR01K07Intergenic splicingGH23964 and othersETS proteins
GTDexp74-#310-2trithorax (trx)Semilethal88B3BACR01H04Intergenic splicingGH06495 and othersMouse Mll human MLL
GTDexp74-#96nebula (nla)Viable89B12-13EP(3)3462Intergenic splicingLD15403 and othersHuman yy37d03.r1
GTDexp1-#31/1brain tumor (brat)Viable37C1-D1BACR48001 BACR10109Intergenic splicingLD28374 and othersHomologous to Caenorhabditis NcI-1 zinc finger
GTDexp74-#310-1bancal hnRNP KLethal57AAC014285Intergenic splicingLD42648 and othersHuman hnRNP K
GTexp7-#6CG17090Female sterile61CDm65A9SIntergenic splicingSD05876 and othersHuman PKY protein kinase
GTexp7-#45UnknownViable55CAE003799Intergenic splicing
GTexp49-2-4UnknownSemilethal86DBACR48E12 BACR06005Intergenic splicing
GTexp16-#8 Fructose 2,6 bisphosphatase Viable17C-DDm11H6SIntergenic splicing and readthrough transcriptionGH24742 and othersFructose bisphosphatases
GTDexp1-#2/2UnknownViable37C1-D1BACR48001 BACR10109Intergenic splicingSD07237
GTDexp1-#24/1 α -mannosidase II Lethal89A1-5BACR48G17Intergenic splicingLD09921 and othersα-Mannosidases
GTDexp1-#1/1UnknownLethal79E4-6Dm1562Intergenic splicing
GTDexp74-#56CG1244Lethal62F1-2BACR22P20-T7Intergenic splicingLD26015 and othersHuman ye89f06.r1
GTDexp74-#94/1UnknownLethal88A-BBACR10E03Intergenic splicingGM07940
GTDexp74-#159-1CG4798Viable54B-CBACR21A09Intergenic splicingLP05522 and othersMouse mg90f12.r1
GTDexp74-#1UnknownLethal56FAC004290Intergenic splicing
GTDexp74-#198UnknownViable89B-CBACR05P04Intergenic splicing
GTDexp74-#135-2UnknownSemilethal87DAC020412Intergenic splicing
GTDexp74-#61-3UnknownViableIntergenic splicing
GTDexp7-#49UnknownNot determined (on CyO)37ABACR25C02 BACR07J05Readthrough transcriptionLD32867 and othersHomologous to mouse FAF
GTDexp7-#11mushroom body expressed (mub)Lethal79B1-2EP (3) 0783 EP (3) 3638Readthrough transcriptionRNA binding proteins
GTDexp74-#159-2CG4798Viable54A1-B5EP(2)2177Readthrough transcriptionLD46226 and others
GTDexp74-#95/1UnknownViable91F1-3BACR48G05 Dm0333Readthrough transcriptionGM10731 GM01567
GTDexpZ-1UnknownSemilethal79BEP(3)3108 EP(3)3623Readthrough transcription
GTDexp74-#77/3UnknownViable68A8-9AC017890Readthrough transcription
GTDexp74-#295-1UnknownLethal61D1-2AC019753Readthrough transcription
GTDexp74-#236UnknownViable68C2-4AC004438Readthrough transcription