TABLE 5

Simulation of chromosome-wise type I error α by quick method for IM in an advanced backross line (BC2), an F2 population, and an advanced intercross population (F3)

Step
size
BC2F2F3
MaDistributionbα = 0.01α = 0.05α = 0.01α = 0.05α = 0.01α = 0.05
100N(0, 1)10.00670.03150.00720.03330.00860.0395
50N(0, 1)10.00630.03300.00720.03740.01000.0414
20N(0, 1)10.00990.03890.00960.04260.01010.0436
10N(0, 1)10.00870.04140.00930.04440.00850.0461
5N(0, 1)10.00810.04470.00990.04800.00870.0456
5N(0, 1)20.00930.04250.00900.04430.00750.0440
5N(0, 1)50.00710.04480.00830.04290.00830.0454
100U(0, 1)10.00690.03450.00710.03280.00920.0425
100Embedded Image 10.00660.03340.00640.03090.00750.0329
20Embedded Image 10.00810.03480.00900.03620.00880.0382
  • Equal spacing of markers is assumed. Simulation is based on 10,000 replications. Length of chromosome = 100 cM.

  • a M, No. of intervals on a chromosome.

  • b N(0, 1), standard normal; U(0, 1), uniform; Embedded Image , chi square with 1 d.f.