TABLE 2

SGS1 synthetic-lethal mutants

Complementation with sgs1 allelesa
Complementation groupNo. of allelesMutant geneSGS1sgs1Δsgs1-hdsgs1-ΔN158sgs1-ΔC200sgs1-ΔC300
SLX18YBR228W+---+-
SLX27MMS4+---+-
SLX36YDR386W+---+-
SLX46YLR135W+---+-
SLX53YDL013W+---+-
SLX63SRS2/HPR5++b+NDNDND
SLX81YER116C+--NDNDND

  • ↵a slxΔ sgs1Δ complementation by the indicated SGS1 allele: +, viable; -, lethal; ND, not done.

  • ↵b srs2Δ sgs1Δ strains are viable but slow growing.