TABLE 1

Mitotic chromosome condensation defects in mus101lcd neuroblasts

GenotypeNo. of brains examineda% aberrant mitosesb (total no. of mitoses examined)
mus101lcd/mus101+ 120 (383)
mus101lcd/mus101lcd 1395 (168)
mus101lcd/Df(1)HA92 3100 (50)
mus101lcd/Y 1280 (103)
  • a Brains were incubated in 10 μm colchicine for 1 hr followed by treatment in hypotonic saline. The appearance of abnormal mitotic figures in mutant brains was similar with and without colchicine treatment (not shown).

  • b Aberrant cells are those exhibiting abnormal condensation of at least one chromosome.