TABLE 3

Comparison of African vs. non-African samples

DD*
LocusnaSbπ (%)cDdD*e10-foldf100-fold10-foldf100-fold
Lp1 Afr.48770.1980.3701.3590–180–11NonegNoneg
Lp1 non-Afr.94600.1731.4051.288NonegNonegNonehNoneh
Ace Afr.10700.1080.228−0.0900–100+0–100+0–100+0–100+
Ace non-Afr.12440.0801.4660.912NonegNoneg0–240–19
Dys44 Afr.115320.0990.776i0–330–19ii
Dys44 non-Afr.135210.0851.950iNonehNonehii
Xq13.3 Afr.23240.035−1.703−1.9757–100+6–100+0–100+0–100+
Xq13.3 non-Afr.47170.031−0.556−1.6740–100+0–100+0–100+0–100+
Duffy Afr.4890.052−0.695−0.6070–100+0–100+0–100+0–100+
Duffy non-Afr.34150.1580.8491.1410–100+0–700–390–25
Dmd44 Afr.10120.1590.5710.5400–100+0–920–100+0–100+
Dmd44 non-Afr.31140.1250.2370.2610–100+0–720–100+0–64
β-globin Afr.103160.098−0.423−0.4680–100+0–100+0–100+0–54
β-globin non-Afr.246140.1652.2510.204NonegNoneg0–100+0–15
Dmd7 Afr.1090.133−0.005−0.5950–100+0–100+0–100+0–100+
Dmd7 non-Afr.3140.011−1.889−3.02214–100+10–100+14–100+10–100+
  • a Sample size.

  • b Number of segregating sites.

  • c Average number of pairwise differences per base pair, in percentage (cf. Tajima 1983).

  • d From Tajima (1989a).

  • e From Fu and Li (1993).

  • f Range of T values for which the observed D falls within the middle 95% of simulated D values. Simulations use a value of C estimated from the data (see materials and methods).

  • g When T = 0 (no growth), the observed D has two-tailed P < 0.01.

  • h When T = 0 (no growth), the observed D has two-tailed P < 0.05.

  • i D* could not be calculated because the data from the original ascertainment sample are unavailable.