TABLE 7

Life span QTL in each sex and density and their additive and dominant effects

SexDensityQTL regionaabdcd/adCandidate genes (cytological positions)
MLow(1) 35B–43A−1.485.46−3.7Adh (35B)
(5) 71E−2.893.38−1.2
(6) 72A–77A4.793.330.7Pgm (72D), Cat (75D)
MHigh(2) 46C–49D6.184.640.7EF1α (48D)
(3) 50D3.455.831.0
FLow(1) 35B–38E−4.203.2−0.8Adh (35B)
(4) 67D–68C3.883.040.8Sod (68A)
(5/6) 69D–87B−3.764.17−1.1Pgm (72D), Cat (75D), Ide (77B), Hsp 70A (87A)
FHigh(4) 67D–68C−5.245.53−1.1Sod (68A)
  • a QTL region defines the range (using cytological positions) over which the likelihood ratio exceeded the significance threshold. Numbers in parentheses indicate the numerical designation of each QTL region. Shared numbers indicate the same QTL.

  • b Additive effects (a) = (A1A1 − A2A2)/2, where A1A1 is the life span phenotype of the lines homozygous for the 2b allele at that QTL, and A2A2 is the life span phenotype of the lines homozygous for the Oregon allele at that locus.

  • c Dominance effects (d) = A1A2a, where A1A2 is the life span phenotype of lines heterozygous at that QTL. d = 0 when the QTL has purely additive effects; when a is (+), d is (+) when the 2b allele is dominant and d is (−) when the Oregon allele is dominant.

  • d Dominance/additive effects (d/a) = 1 or −1 given complete dominance, d < 1 or > −1 given partial dominance; d > a or d < −1 indicates overdominance (d/a > |1|).