TABLE 3

Genetic complementation of elave5 and elavts1 by domain replacement transgenes

elave5elavts1
TransgeneLineNo. rescued malesNo. control femalesRescue (%)No. rescued malesNo. control femalesRescue (%)No. ts1 males
ER129264676219326670
2A174554163252650
2B09300186100
ER122A04360034600
2B04810029100
5202270029900
ER32A26729790245370660
EH32A22233965342354972
ES1/23A6949014253359701
3B122433282282549013
428023035145191763
ES13A549002634583
4233800031002
4551700031000
ES220514053312170
2A16337531284110
3A04830526120
ES123A04400030500
2503550027300
3204260029000
  • Transgenes encoding mutant proteins were tested for functional complementation with elav alleles: elave5 and elavts1 w/Y; Tg/balancer were crossed to elavxw sn/balancer (x denotes the elav allele, Tg stands for the transgene). Rescue (%) = (number of rescued males of genotype elavx w sn/Y; Tg/+)/(number of control females of genotype elavxw sn/w; Tg/+) × 100. For details see materials and methods.