TABLE 2

The lin-13 null phenotype

Genotype of progenyGenotype of motherTemperatureMuvL2 arrestSterile
N2N225°NoNoNo
lin-13(n387)alin-13/+25°YesNoYes
lin-13(RNAi)bN2c25°YesYesYes
N2N215°NoNoNo
lin-13(n387)lin-13/+15°NoNoNo
lin-13(n387)lin-13(n387)15°NoNoYes
lin-13(RNAi)dN2c15°NoNoYes
N2N215° → 25°NoNoNo
lin-13(n387)lin-13(n387)15° → 25°eYesYesYes
  • lin-13(n387) is marked with unc-36(e251). The data in this table are based on Ferguson and Horvitz (1985, 1989) and this study.

  • a Hermaphrodites also grow slowly.

  • b Data are described in the text.

  • c The maternal contribution of lin-13 may be depleted in the progeny of these injected hermaphrodites.

  • d Hermaphrodites have a protruding vulva but are not Multivulva.

  • e Gravid lin-13(n387) hermaphrodites segregated from lin-13/+ parents at 15° were shifted to 25°, and the embryos were hatched and maintained at 25°. Most of these embryos developed until the L2 stage and arrested, but some became sterile Multivulva adults.