TABLE 5

Precision of QTL position estimates with varying numbers of generations since the mutation

Bracket size (cM): 1Hp(NG)aHp(100)a
0.50.2510.50.25
NG = 2000.620.640.620.600.620.68
1000.700.620.68Same as H(NG)
500.660.560.340.700.600.30
100.320.300.280.480.500.36
  • The fraction of the replicated simulations, where the estimate of the QTL position was in the correct bracket or in a bracket next to the correct bracket, is shown. The number of generations since the mutation at the QTL occurred (AG) is varied; the effective size of the population was 100; and the frequency of the QTL in the last generation was >0.1.

  • a Hp(x) denotes that the matrix of (co)variances of haplotype effects is estimated assuming that the mutation occurred x generations ago.