TABLE 6

Partial rescue of recessive lethality of mod(mdg4) alleles in the presence of the transgene P (w+7.5kb BamHI)

Males
Femalesaneo12902rev32040607
P (w+7.5kb BamHI); mod(mdg4)neo129slslslslbb
P (w+7.5kb BamHI); mod(mdg4)02slslbbb
  • a Wm4 females carrying the P (w+ 7.5kb BamHI) transgene and the indicated mod(mdg4) allele balanced over TM3, Sb Ser were crossed to heterozygous Wm4/Y; mod(mdg4)/TM3 males. For viability: −, lethal, on average <5% of the expected progeny survive to eclose as adults; sl, semilethal, on average 5–50% of the expected progeny survive to eclose as adults; all trans-heterozygous flies are w+ in phenotype, indicating the presence of the transgene.

  • b Trans-heterozygotes with a frequency of 1–3% adults eclosed; without the transgene, no trans-heterozygous escapers were found.