TABLE 2

PEV enhancer effect and homeotic effects of mod(mdg4) mutations

AlleleEnhancer effecta (R1)Paternal effectb (R2)ViabilityHomeotic transformation of A5 to A4cOrigin
mod(mdg4)neo129+ + (0.17)+ (0.47)94.2(73)P-induced
mod(mdg4)R32+ + + (0.05)+ + (0.26)96.4(86)Revertant of neo129
mod(mdg4)02+ + (0.16)+ (0.65)28.8(52)Spontaneous
mod(mdg4)03+ + (0.16)+ + (0.15)100(43)P-induced
mod(mdg4)04+ + + (0.07)+ (0.52)50.1(96)Spontaneous
mod(mdg4)05+ (0.32)+ (0.69)55.7(61)P-induced
mod(mdg4)06+ + + (0.05)+ + (0.33)17.7(113)EMS
mod(mdg4)07+ + + (0.04)+ + (0.24)13.4(127)EMS
142.4 Δ32+ + + (0.03)+ + + (0.03)NDdNDRev. of P(w+) 142d
DfGC14+ (0.30)− (0.79)12.7(94)Deficiencyd
  • The strength of the PEV enhancement and the paternal effect have been classified as strong (+ + +; R < 0.10), intermediate (+ + ; R between 0.10 and 0.30), and weak (+; R between 0.30 and 0.75) alleles; R > 0.75 represents no significant effect.

  • a The enhancement of PEV was determined by measuring the absorbance of extracted red eye pigment of wm4/Y males containing the mod(mdg4) allele and the suppressor mutation Su(var)2-101 at 480 nm. These offspring males were obtained in a cross of wm4; Cy/apXa; Su(var)2-101/Sb females to Wm4/Y; mod(mdg4)/TM3 males. (R1) represents the ratio of eye pigment content of Wm4; + /apXa Su(var)2-101/mod(mdg4) males and Wm4; + /apXa Su(var)2-101/ + males obtained in an independent cross of wm4; Cy/apXa Su(var)2-101/Sb females to Wm4/Ymales.

  • b Paternal enhancer effects were studied in Wm4; +/apXa Su(var)2-101/TM3 offpring males produced by a cross of Wm4; Cy/apXa Su(var)2-101/Sb females to Wm4/Y; mod(mdg4)/TM3 males. (R2) represents the ratio of eye pigment content of wm4; +/apXa Su(var)2-101/TM3 males obtained in a cross of wm4; Cy/apXa Su(var)2-101/Sb females to Wm4/Y; mod(mdg4)/TM3 males and wm4; + /apXa Su(var)2-101/ + males obtained in an independent cross of wm4; Cy/apXa Su(var)2-101/Sb females to Wm4/Ymales.

  • c Homeotic transformation of A5 to A4 was determined by examination of trans-heterozygous Df(3R)redtrx/ mod(mdg4) males obtained in a cross of Df(3R)redtrx/TM3, Ser females to mod(mdg4) /TM3, Sb Ser males. Percentage of transformed flies is given; number of males examined is shown in parentheses.

  • d Mutations mod(mdg4)06 and mod(mdg4)07 were obtained from M. Frasch, and P142Δ32 and Df(3R)GC14 are described in Azpiazu and Frasch (1993) and Mohler and Pardue (1984), respectively. The P142Δ32mutation was induced on a TM3, Sb Δ2–3 chromosome.