TABLE 3

Comparison of amino acid substitutions in the Su(var) HDAC1 group with conserved regions in human and yeast homologues

HDAC1313 R30CHDAC1303 HDAC1328 C98YHDAC1326 P204S
D. melanogasterGHPMKPHRIRMFNVGEDCPVFDGLSFHKYGEYFPGTG
HDAC1 mutant strain-------C---------Y---------------S---
Homo sapiens HDAC1-------R---------C---------------P---
S. cerevisiae RPD3-------R-------D-C-------------F-P---
  • A dashed line indicates identity.