TABLE 2

Lethal phase analysis of mutations in HDAC1: percentage of animals that die at the indicated developmental stage

Mutant strain testedEmbryonic lethalityLarval lethalityPupal lethalityMale viabilitya
HDAC1def86.824.73.993
HDAC1def246.325.97.691
HDAC13033.913.317.071
HDAC13133.428.42.351
HDAC13262.930.76.588
HDAC13284.116.416.878
  • a Viability of males expected to survive as compared to their female siblings.