QTL R^{2} distribution | ||||
---|---|---|---|---|
cv_{i} and m_{i} distributions | Average (%) | Sum (%) | Skewness | Percentage under 2% |
∀i, cv_{i}, = 0.2 | ||||
∀i, m_{i} = m (reference) | 1.99 | 99.5 | — | 100.0 |
m_{i}: normal | 1.99 | 99.3 | 4.86 | 67.4 |
m_{i}: exponential | 1.99 | 99.3 | 21.02 | 76.2 |
m_{i}: uniform | 1.97 | 98.4 | 7.12 | 89.0 |
cv_{i}: normal distribution | ||||
∀i, m_{i} = m (reference) | 1.96 | 98.2 | 3.46 | 68.4 |
m_{i} : normal | 1.96 | 98.1 | 9.25 | 71.8 |
m_{i} : exponential | 1.96 | 98.2 | 13.66 | 74.1 |
m_{i} : uniform | 1.90 | 95.1 | 6.90 | 90.6 |
cv_{i} : gamma distribution | ||||
∀i, m_{i} = m (reference) | 1.99 | 99.7 | 6.95 | 76.2 |
m_{i} : normal | 1.99 | 99.7 | 8.30 | 78.0 |
m_{i} : exponential | 1.99 | 99.7 | 9.21 | 77.4 |
m_{i} : uniform | 1.99 | 99.4 | 7.07 | 90.9 |
The R^{2} distributions were computed for a 50-enzyme pathway in 100 F_{2} populations, with four distributions of average activity (m_{1}) reference (same m_{t} for all the QTL), normal, exponential, and uniform; and three distributions of coefficients of genetic variation (cv_{t}), same cv_{t} for all the QTL, normal, and gamma. Mean R^{2} value of the distribution and average sum of the 50 R^{2} are in percentage of total flux variance.