TABLE 3

General phenotypic characteristics of the msc mutant classes

Meiotic
Unequal SCR
Disome segregationGeneral
description
EquationalReductionalAberrant
Class I
    RED12- to 6-fold increaseIncreasedReducedReducedMeiotic recombination checkpoint genes
    MEK1
    RAD24Avg. 3.8-fold
    RAD17
    MEC3
    MSC6
Class II
    DMC12.7- to 6-fold increaseIncreasedReducedReducedDominant meiotic lethal
    ELA1
    INP52Avg. 3.8-fold
    MSC1
    MSC3
    Linkage not yet confirmeda
    BUD3
    PET122
    Null mutant not elevatedb
    UBR1
    MSC2
Class III1.8- to 5-fold increaseSlightly reducedIncreasedSlightly reducedMeiotic hyper-rec
    MNR2
    MSC7Avg. 3.1-fold
  • a Linkage of the msc phenotype to the transposon insertion at these loci has not yet been confirmed.

  • b Reconstruction experiments revealed that the null mutant did not exhibit the msc phenotype.