TABLE 1

Major operon gains in P. furiosus

Putative operon functionsNo. of Pfu ORFsPho ORF junction
Amino acid biosynthesis: pyruvate family9PH0696-PH0697
Amino acid biosynthesis: aromatic family11PH1710-PH1711
Amino acid biosynthesis: aromatic family5PH1714-PH1715
Amino acid biosynthesis: glutamate family4PH1949-PH1950
Degradation of polysaccharides2PH1501-PH1502
Energy metabolism: TCA cycle3PH1949-PH1950
Transport and binding proteins: carbohydrates6PH0281-PH0283
Transport and binding proteins: general5PH0303-PH0305
Transport and binding proteins: anions10PH0643-PH0644
Transport and binding proteins: cations5PH0766-PH0768
Transport and binding proteins: general5PH1062-PH1063
Transport and binding proteins: general7PH1242-PH1243
Transport and binding proteins: general6PH1353-PH1354
Transport and binding proteins: carbohydrates6PH1686-PH1690
Conserved hypothetical proteins5PH0694-PH0695
Conserved hypothetical proteinsa8PH0828-PH0830
Conserved hypothetical proteins7PH1251-PH1252
  • This table contains the major insertion/deletion segments from the P. furiosus genome that have colinear ORFs in the P. horikoshii genome. The putative operon functions represent the major functional classification of the Pfu-specific ORFs on the basis of similarity matches to ORFs of known function, except for the conserved hypothetical proteins. This class has significant similarity to known sequence of unknown function.

  • a Colinear with Methanococcus jannaschii ORFS MJ379 to MJ385.