TABLE 4

Stimulation of SCE by UV in DUN1 and the dun1 mutant

Stimulation in DUN1 (YD122)aStimulation in dun1 (YD124)a
UV DoseSurvival %His+/CFU × 107bSurvival %His+/CFU × 107bRatioc
    60 J/m29798 ± 3671216 ± 362.2
    90 J/m287142 ± 2353335 ± 892.4
    120 J/m277166 ± 5645343 ± 982.1
After Nocodazole
    60 J/m29885 ± 508685 ± 71.0
    90 J/m297130 ± 11394125 ± 631.0
  • a For complete genotype, see Table 1.

  • b His+/CFU × 107 = (His+ frequency w/agent – His+ spontaneous frequency) × 107; N = 6. Spontaneous frequency of YD122 = 1.6 × 10–5, spontaneous frequency for YD124 = 2.2 × 10–5.

  • c (His+ per 107 CFU for dun1)/(His+ per 107 CFU for DUN1).